When a patient is suspected of having amyloidosis, a series of examinations need to be carried out to confirm whether any amyloid deposits are present. A positive histological test is necessary to confirm the amyloidosis diagnosis. If the histopathological test comes back negative, the possibility of having amyloidosis is not automatically disregarded; rather this means that the amyloid deposits could be distributed randomly. In this case, the doctor will request another biopsy (either in the same organ or targeting another).

If amyloidosis is confirmed, further tests are necessary to:

• Confirm the type of amyloidosis

• Detect damage to the brain, heart or kidneys

• Track the illness’s development