What is amyloidosis?
Définition
Amyloidosis is an illness characterised by the accumulation of insoluble fibrous proteins in different tissues, which gradually alters these tissues’ structure and function. The type of amyloidosis depends on the biochemistry of the protein in the amyloid and on the clinical signs observed.
Amyloidosis is an illness characterised by the accumulation of insoluble fibrous proteins in different tissues, which gradually alters these tissues’ structure and function. The type of amyloidosis depends on the biochemistry of the protein in the amyloid and on the clinical signs observed.
Diagram of proteins
The main types of amyloidosis are:
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AL Amyloidosis of the blood (caused by deposits of antibodies aka immunoglobulins)
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Hereditary Amyloidosis (mainly TTR amyloidosis)
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AA Amyloidosis (rare and caused by deposits of inflamed proteins)