{"id":7621,"date":"2026-01-30T14:23:06","date_gmt":"2026-01-30T13:23:06","guid":{"rendered":"https:\/\/reseau-amylose.org\/jesuissoignant\/?page_id=7621"},"modified":"2026-01-30T16:28:54","modified_gmt":"2026-01-30T15:28:54","slug":"depister-lamylose-cardiaque-attr-chez-les-femmes","status":"publish","type":"page","link":"http:\/\/reseau-amylose.org\/jesuissoignant\/depister-lamylose-cardiaque-attr-chez-les-femmes\/","title":{"rendered":"D\u00e9pister l\u2019amylose cardiaque ATTR chez les femmes"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"7621\" class=\"elementor elementor-7621\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8db9119 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8db9119\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-810a13d\" data-id=\"810a13d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-892ae47 elementor-widget elementor-widget-heading\" data-id=\"892ae47\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Optimiser le d\u00e9pistage de l\u2019amylose cardiaque ATTR chez les femmes<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-316a714 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"316a714\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cb1b62e\" data-id=\"cb1b62e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4b6a6a2 elementor-widget elementor-widget-heading\" data-id=\"4b6a6a2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">R\u00e9duire le retard diagnostic chez les patientes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3eefd7c elementor-widget elementor-widget-text-editor\" data-id=\"3eefd7c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>L\u2019<strong>amylose cardiaque ATTR<\/strong> touche autant les femmes que les hommes, mais reste souvent <strong>diagnostiqu\u00e9e plus tard chez les femmes<\/strong>. Les causes principales :<\/p><ul><li>Signes moins typiques et discrets<\/li><li>Seuils \u00e9chographiques bas\u00e9s sur des populations masculines<\/li><li>Biomarqueurs interpr\u00e9t\u00e9s sans tenir compte du sexe<\/li><li>Manifestations extracardiaques attribu\u00e9es \u00e0 l\u2019\u00e2ge<\/li><\/ul><p>Une <strong>vigilance accrue et des seuils adapt\u00e9s<\/strong> permettent de r\u00e9duire nettement les retards diagnostiques.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e027380 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e027380\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d1b811d\" data-id=\"d1b811d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-adabd33 elementor-widget elementor-widget-heading\" data-id=\"adabd33\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Sp\u00e9cificit\u00e9s cardiaques chez les femmes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a94a26 elementor-widget elementor-widget-text-editor\" data-id=\"4a94a26\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong>Hypertrophie souvent moins marqu\u00e9e<\/strong> : un septum entre 10\u201312 mm peut \u00eatre anormal, seuil de 11 mm recommand\u00e9.<\/li><li><strong>Fraction d\u2019\u00e9jection longtemps normale<\/strong>, donnant une fausse impression de normalit\u00e9.<\/li><li><strong>VG plus petit<\/strong>, pouvant rassurer \u00e0 tort.<\/li><\/ul><p>Apr\u00e8s 65\u201370 ans, toute femme pr\u00e9sentant des signes de <strong>R\u2019EPOF<\/strong> ou des anomalies biologiques doit b\u00e9n\u00e9ficier d\u2019un d\u00e9pistage cibl\u00e9.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-42d1172 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"42d1172\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-79efef8\" data-id=\"79efef8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-54be88d elementor-widget elementor-widget-heading\" data-id=\"54be88d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Manifestations extracardiaques pr\u00e9coces<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e702b19 elementor-widget elementor-widget-text-editor\" data-id=\"e702b19\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>De nombreuses manifestations apparaissent 5 \u00e0 10 ans avant les signes cardiaques :<\/p><ul><li>Canal carpien<\/li><li>Dupuytren<\/li><li>Canal lombaire \u00e9troit<\/li><li>Rupture du tendon long du biceps<\/li><\/ul><p>Ces signes doivent \u00eatre <strong>int\u00e9gr\u00e9s dans l\u2019\u00e9valuation cardiologique<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7896aec elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7896aec\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8f21dd4\" data-id=\"8f21dd4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-302f1c9 elementor-widget elementor-widget-heading\" data-id=\"302f1c9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Comment rep\u00e9rer l\u2019amylose chez les femmes vs les hommes ?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c2e8bd9 elementor-widget elementor-widget-text-editor\" data-id=\"c2e8bd9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<table width=\"925\"><tbody><tr><td width=\"281\"><p><b>\u00c9l\u00e9ment compar\u00e9<\/b><\/p><\/td><td width=\"323\"><p><b>Femmes<\/b><\/p><\/td><td width=\"320\"><p><b>Hommes<\/b><\/p><\/td><\/tr><tr><td width=\"281\"><p><b>\u00c2ge au diagnostic<\/b><\/p><\/td><td width=\"323\"><p>Souvent plus tardif, en partie \u00e0 cause d\u2019un d\u00e9pistage insuffisant<\/p><\/td><td width=\"320\"><p>Plus pr\u00e9coce car suspicion plus fr\u00e9quente<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Hypertrophie<\/b><\/p><\/td><td width=\"323\"><p>Moins marqu\u00e9e ; septum souvent 10\u201312 mm ; seuil anormal d\u00e8s 11 mm<\/p><\/td><td width=\"320\"><p>Hypertrophie plus franche ; seuil classique 12 mm<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Taille du VG<\/b><\/p><\/td><td width=\"323\"><p>Plus petit, donnant une impression rassurante<\/p><\/td><td width=\"320\"><p>VG plus volumineux et hypertrophique<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Fraction d\u2019\u00e9jection<\/b><\/p><\/td><td width=\"323\"><p>Longtemps normale malgr\u00e9 une infiltration avanc\u00e9e<\/p><\/td><td width=\"320\"><p>Peut diminuer plus t\u00f4t dans l\u2019\u00e9volution<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Strain<\/b><b> (GLS)<\/b><\/p><\/td><td width=\"323\"><p>Plus alt\u00e9r\u00e9 que la LVEF ; meilleur indicateur<\/p><\/td><td width=\"320\"><p>Alt\u00e9r\u00e9 mais souvent plus coh\u00e9rent avec la LVEF<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Scintigraphie<\/b><\/p><\/td><td width=\"323\"><p>Fixation parfois discr\u00e8te ; risque de faux n\u00e9gatif relatif<\/p><\/td><td width=\"320\"><p>Fixation souvent plus intense<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Biomarqueurs<\/b><\/p><\/td><td width=\"323\"><p>Troponine plus \u00e9lev\u00e9e au diagnostic, augmente t\u00f4t ; NT-proBNP souvent \u00e9lev\u00e9 pr\u00e9cocement<\/p><\/td><td width=\"320\"><p>Troponine et NT-proBNP augmentent plus tardivement pour un m\u00eame niveau d\u2019infiltration<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Sympt\u00f4mes<\/b><\/p><\/td><td width=\"323\"><p>Fatigue fr\u00e9quente ; dysautonomie ; effort limit\u00e9 ;<\/p><p>douleurs diffuses<\/p><\/td><td width=\"320\"><p>Sympt\u00f4mes plus typiques d\u2019insuffisance cardiaque<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Signes extracardiaques<\/b><\/p><\/td><td width=\"323\"><p>Canal carpien, Dupuytren, canal lombaire \u00e9troit, biceps, neuropathie discr\u00e8te<\/p><\/td><td width=\"320\"><p>Signes proches mais souvent identifi\u00e9s plus t\u00f4t<\/p><\/td><\/tr><tr><td width=\"281\"><p><b>Mode de d\u00e9c\u00e8s<\/b><\/p><\/td><td width=\"323\"><p>Davantage de morts subites malgr\u00e9 une hypertrophie moindre<\/p><\/td><td width=\"320\"><p>D\u00e9c\u00e8s plus li\u00e9s \u00e0 progression de l\u2019insuffisance cardiaque<\/p><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-017f294 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"017f294\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e006f04\" data-id=\"e006f04\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d475552 elementor-widget elementor-widget-heading\" data-id=\"d475552\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Biologie : sp\u00e9cificit\u00e9s f\u00e9minines<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ee21282 elementor-widget elementor-widget-text-editor\" data-id=\"ee21282\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<\/p><ul><li><strong>Troponine<\/strong> : souvent plus \u00e9lev\u00e9e que chez l\u2019homme au diagnostic, augmente t\u00f4t, pr\u00e9dicteur du risque de d\u00e9c\u00e8s, m\u00eame sans hypertrophie visible.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>NT-proBNP<\/strong> : \u00e9l\u00e9vation fr\u00e9quente avant l\u2019apparition d\u2019une hypertrophie.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Association clinique<\/strong> : NT-proBNP \u00e9lev\u00e9 + fatigue + petit VG + strain alt\u00e9r\u00e9 = indication forte de scintigraphie.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-28bf074 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"28bf074\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0bbe708\" data-id=\"0bbe708\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dc3441f elementor-widget elementor-widget-heading\" data-id=\"dc3441f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Pronostic : \u00e9l\u00e9ments essentiels pour les soignants<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75e8b94 elementor-widget elementor-widget-text-editor\" data-id=\"75e8b94\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<\/p><ul><li><strong>Avant 77 ans<\/strong> : formes souvent plus agressives, GLS tr\u00e8s alt\u00e9r\u00e9, LVEF diminu\u00e9e, biomarqueurs \u00e9lev\u00e9s, risque accru d\u2019\u00e9v\u00e9nements graves.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Apr\u00e8s 77 ans<\/strong> : fonction systolique meilleure, strain mieux pr\u00e9serv\u00e9, progression plus lente, mais incidence plus \u00e9lev\u00e9e de <strong>mort subite<\/strong>.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Surveillance rythmologique renforc\u00e9e<\/strong> recommand\u00e9e.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8710ece elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8710ece\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-518cb55\" data-id=\"518cb55\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a857a4f elementor-widget elementor-widget-heading\" data-id=\"a857a4f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Imagerie : cl\u00e9s d\u2019interpr\u00e9tation<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b87a6a8 elementor-widget elementor-widget-text-editor\" data-id=\"b87a6a8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<\/p><ul><li>Septum \u226511 mm doit \u00eatre consid\u00e9r\u00e9 comme anormal chez la femme.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Strain longitudinal global<\/strong> : indicateur le plus sensible, alt\u00e9r\u00e9 avant la fraction d\u2019\u00e9jection.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>LVEF<\/strong> : peut rester normale malgr\u00e9 infiltration avanc\u00e9e.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Aspect d\u2019apical sparing<\/strong> \u00e0 rechercher syst\u00e9matiquement.<\/li><\/ul><p>\u00a0<\/p><ul><li><strong>Scintigraphie<\/strong> : fixation parfois discr\u00e8te, ne doit pas exclure le diagnostic.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b4f0300 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b4f0300\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-d1cced0\" data-id=\"d1cced0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d585ae1 elementor-widget elementor-widget-heading\" data-id=\"d585ae1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Outil R\u2019EPOF pour le d\u00e9pistage f\u00e9minin<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1253594 elementor-widget elementor-widget-text-editor\" data-id=\"1253594\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><strong>R \u2013 Atteintes rhumatologiques pr\u00e9coces<\/strong> : canal carpien, Dupuytren, canal lombaire \u00e9troit, rupture du long biceps, arthropathies pr\u00e9coces.<\/li><li><strong>E \u2013 Essoufflement inexpliqu\u00e9<\/strong>, souvent attribu\u00e9 \u00e0 l\u2019\u00e2ge ou au d\u00e9conditionnement.<\/li><li><strong>P \u2013 Prise de poids rapide<\/strong>, li\u00e9e \u00e0 une r\u00e9tention hydrique pr\u00e9coce.<\/li><li><strong>O \u2013 \u0152d\u00e8mes<\/strong> des membres inf\u00e9rieurs.<\/li><li><strong>F \u2013 Fatigue persistante<\/strong>, fr\u00e9quente et parfois premier signe.<\/li><\/ul><p>M\u00eame une pr\u00e9sence incompl\u00e8te de R\u2019EPOF doit faire <strong>suspecter une amylose ATTRwt<\/strong>.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-4309a03\" data-id=\"4309a03\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-daae819 elementor-widget elementor-widget-image\" data-id=\"daae819\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"782\" height=\"1024\" src=\"http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF-782x1024.png\" class=\"attachment-large size-large wp-image-7624\" alt=\"\" srcset=\"http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF-782x1024.png 782w, http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF-229x300.png 229w, http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF-768x1005.png 768w, http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF-1174x1536.png 1174w, http:\/\/reseau-amylose.org\/jesuissoignant\/wp-content\/uploads\/sites\/5\/2026\/01\/REPOF.png 1425w\" sizes=\"(max-width: 782px) 100vw, 782px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9264912 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9264912\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-44b7f13\" data-id=\"44b7f13\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-212d398 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"212d398\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/reseau-amylose.org\/jesuissoignant\/documentation\/triptyques-du-centre-de-reference-des-amyloses-cardiaques-chu-henri-mondor\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">T\u00e9l\u00e9chargez notre brochure pour votre consultation<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-6c08d52\" data-id=\"6c08d52\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-15f713c elementor-align-center elementor-widget elementor-widget-button\" data-id=\"15f713c\" data-element_type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/reseau-amylose.org\/jesuispatient\/triptyques-du-centre-de-reference-des-amyloses-cardiaques-chu-henri-mondor\/\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">T\u00e9l\u00e9chargez notre brochure \u00e0 distribuer \u00e0 vos patients<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cc05791 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cc05791\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1587ad7\" data-id=\"1587ad7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2b584b9 elementor-widget elementor-widget-text-editor\" data-id=\"2b584b9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>L \u2019 amylose cardiaque n\u2019est pas une maladie r\u00e9serv\u00e9e aux hommes.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Optimiser le d\u00e9pistage de l\u2019amylose cardiaque ATTR chez les femmes R\u00e9duire le retard diagnostic chez les patientes L\u2019amylose cardiaque ATTR touche autant les femmes que les hommes, mais reste souvent diagnostiqu\u00e9e plus tard chez les femmes. Les causes principales : Signes moins typiques et discrets Seuils \u00e9chographiques bas\u00e9s sur des populations masculines Biomarqueurs interpr\u00e9t\u00e9s sans [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-7621","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>D\u00e9pister l\u2019amylose cardiaque ATTR chez les femmes<\/title>\n<meta name=\"description\" content=\"Amylose cardiaque ATTR chez les femmes : sp\u00e9cificit\u00e9s cliniques et biologiques, R\u2019EPOF... pour un d\u00e9pistage pr\u00e9coce.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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